Microparticles in Immune-Mediated Diseases: Roles in Autoimmunity, Autoinflammation, Sepsis, and Immunodeficiency (2024)

About this Research Topic

Manuscript Summary Submission Deadline 03 March 2025

Manuscript Submission Deadline 02 May 2025

Guidelines

Microparticles (MPs) are essential mediators of cellular communication, possessing the ability to transfer proteins, lipids and nucleic acids between cells. These small membranous structures are produced by various cell types in both physiological and pathological conditions, influencing not only neighboring but also distant cells in different organs and tissues. Their role is particularly crucial in the context of immune-mediated diseases, where they significantly contribute to the regulation of immune responses, inflammation, and cellular homeostasis. The study of MPs offers potential breakthroughs in the understanding of complex diseases such as autoimmune and autoinflammatory disorders, sepsis, and immunodeficiencies. By analyzing MPs it is possible to gain insights into disease mechanisms and progression, identify potential biomarkers for early diagnosis, and explore novel therapeutic targets. This background prepares the ground to discuss the multifaceted impacts of MPs in immune regulation and their emerging significance in medical research and clinical practice.

This Research Topic is dedicated to capturing and synthesizing the latest innovations in the field of microparticles (MPs) and their interactions with the immune system. MPs play a crucial role in modulating a broad spectrum of immune responses, including those involved in autoimmune disorders, immunodeficiencies, and sepsis. Despite their importance, the specific mechanisms by which MPs influence these complex immune conditions are not fully understood. Furthermore, the literature presents conflicting data regarding their exact roles, contributing to continued ambiguity in the field.

Recent technological advances have improved our ability to study MPs, but there remains a lack of standardized methods to isolate, identify, and analyze their content. This special issue aims to fill these gaps by encouraging submissions that push the boundaries of current research. We are looking for contributions that offer new perspectives and methodologies to study MPs, their functional roles, and their potential as diagnostic and therapeutic targets in the field of autoimmunity.

Through this collection, we intend to stimulate further research and clarify the role of MPs in immune regulation, shedding light on their multiple functions in various immune-mediated conditions and paving the way for new scientific investigations and clinical applications.

This Research Topic focuses on the roles of microparticles (MPs) in the immune system, particularly their effects on various immune responses. We invite submissions on the following topics:

-Mechanisms of MP Influence: Explorations the role of MPs in modulating immune responses in autoimmune diseases, immunodeficiencies, sepsis, allergies, and cancer.

-Diagnostic Applications: Research on MPs as biomarkers for early diagnosis, disease monitoring, and prognosis in immune-mediated diseases.

-Therapeutic Innovations: Studies on the potential of MPs as therapeutic targets, including novel MP-based treatments.

-Technological Advances: Articles on new methods for isolating, identifying, and analyzing MPs, with a focus on imaging and bioinformatics.

Manuscript Types Sought:

•Original Research Articles

•Review Articles

•Short Communications

Microparticles in Immune-Mediated Diseases: Roles in Autoimmunity, Autoinflammation, Sepsis, and Immunodeficiency (1)

Keywords:Microparticles; autoimmunity; autoinflammatory diseases; sepsis; allergy; immunovigilance; biomarkers


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Microparticles (MPs) are essential mediators of cellular communication, possessing the ability to transfer proteins, lipids and nucleic acids between cells. These small membranous structures are produced by various cell types in both physiological and pathological conditions, influencing not only neighboring but also distant cells in different organs and tissues. Their role is particularly crucial in the context of immune-mediated diseases, where they significantly contribute to the regulation of immune responses, inflammation, and cellular homeostasis. The study of MPs offers potential breakthroughs in the understanding of complex diseases such as autoimmune and autoinflammatory disorders, sepsis, and immunodeficiencies. By analyzing MPs it is possible to gain insights into disease mechanisms and progression, identify potential biomarkers for early diagnosis, and explore novel therapeutic targets. This background prepares the ground to discuss the multifaceted impacts of MPs in immune regulation and their emerging significance in medical research and clinical practice.

This Research Topic is dedicated to capturing and synthesizing the latest innovations in the field of microparticles (MPs) and their interactions with the immune system. MPs play a crucial role in modulating a broad spectrum of immune responses, including those involved in autoimmune disorders, immunodeficiencies, and sepsis. Despite their importance, the specific mechanisms by which MPs influence these complex immune conditions are not fully understood. Furthermore, the literature presents conflicting data regarding their exact roles, contributing to continued ambiguity in the field.

Recent technological advances have improved our ability to study MPs, but there remains a lack of standardized methods to isolate, identify, and analyze their content. This special issue aims to fill these gaps by encouraging submissions that push the boundaries of current research. We are looking for contributions that offer new perspectives and methodologies to study MPs, their functional roles, and their potential as diagnostic and therapeutic targets in the field of autoimmunity.

Through this collection, we intend to stimulate further research and clarify the role of MPs in immune regulation, shedding light on their multiple functions in various immune-mediated conditions and paving the way for new scientific investigations and clinical applications.

This Research Topic focuses on the roles of microparticles (MPs) in the immune system, particularly their effects on various immune responses. We invite submissions on the following topics:

-Mechanisms of MP Influence: Explorations the role of MPs in modulating immune responses in autoimmune diseases, immunodeficiencies, sepsis, allergies, and cancer.

-Diagnostic Applications: Research on MPs as biomarkers for early diagnosis, disease monitoring, and prognosis in immune-mediated diseases.

-Therapeutic Innovations: Studies on the potential of MPs as therapeutic targets, including novel MP-based treatments.

-Technological Advances: Articles on new methods for isolating, identifying, and analyzing MPs, with a focus on imaging and bioinformatics.

Manuscript Types Sought:

•Original Research Articles

•Review Articles

•Short Communications

Microparticles in Immune-Mediated Diseases: Roles in Autoimmunity, Autoinflammation, Sepsis, and Immunodeficiency (2)

Keywords:Microparticles; autoimmunity; autoinflammatory diseases; sepsis; allergy; immunovigilance; biomarkers


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Microparticles in Immune-Mediated Diseases: Roles in Autoimmunity, Autoinflammation, Sepsis, and Immunodeficiency (2024)
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